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Structure paper

TitleStructure of the Tdp-Epi-Vancosaminyltransferase Gtfa from the Chloroeremomycin Biosynthetic Pathway.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 100, Page 9238-, Year 2003
Publish dateJun 12, 2003 (structure data deposition date)
AuthorsMulichak, A.M. / Losey, H.C. / Lu, W. / Wawrzak, Z. / Walsh, C.T. / Garavito, R.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:12874381
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1pn3:
Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and the acceptor substrate DVV.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1pnv:
Crystal Structure of TDP-epi-Vancosaminyltransferase GtfA in complexes with TDP and Vancomycin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-TYD:
THYMIDINE-5'-DIPHOSPHATE

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • amycolatopsis orientalis (bacteria)
KeywordsTRANSFERASE/ANTIBIOTIC / GT-B GLYCOSYLTRANSFERASE / ROSSMANN FOLD / GLYCOPEPTIDE / VANCOMYCIN / ANTIBIOTIC / TRANSFERASE-ANTIBIOTIC COMPLEX

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