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TitleRole of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Journal, issue, pagesBiochem. J., Vol. 375, Page 339-349, Year 2003
Publish dateJul 22, 2003 (structure data deposition date)
AuthorsFontes, M.R.M. / Teh, T. / Toth, G. / John, A. / Pavo, I. / Jans, D.A. / Kobe, B.
External linksBiochem. J. / PubMed:12852786
MethodsX-ray diffraction
Resolution2.3 - 2.5 Å
Structure data

PDB-1q1s:
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1q1t:
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsPROTEIN TRANSPORT / importin alpha/karyopherin alpha / nuclear localisation sequence (NLS) recognition / phosphorylation / simian virus (SV40) large tumor-antigen (T-antigen) NLS / X-ray crystal structure

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