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Structure paper

TitleRedox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate
Journal, issue, pagesNature, Vol. 423, Page 769-, Year 2003
Publish dateMar 28, 2003 (structure data deposition date)
AuthorsSalmeen, A. / Andersen, J.N. / Myers, M.P. / Meng, T.C. / Hinks, J.A. / Tonks, N.K. / Barford, D.
External linksNature / PubMed:12802338
MethodsX-ray diffraction
Resolution1.8 - 2.15 Å
Structure data

PDB-1oem:
PTP1B with the catalytic cysteine oxidized to a sulfenyl-amide bond
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-1oeo:
PTP1B with the catalytic cysteine oxidized to sulfonic acid
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PHOSPHORYLATION / PHOSPHATASE / CYSTEINE SULFONIC ACID

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