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TitleX-ray Structure Determination of Trypanosoma brucei Ornithine Decarboxylase Bound to D-Ornithine and to G418: INSIGHTS INTO SUBSTRATE BINDING AND ODC CONFORMATIONAL FLEXIBILITY.
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 22037-22043, Year 2003
Publish dateDec 31, 2002 (structure data deposition date)
AuthorsJackson, L.K. / Goldsmith, E.J. / Phillips, M.A.
External linksJ. Biol. Chem. / PubMed:12672797
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-1njj:
Crystal structure determination of T. brucei ornithine decarboxylase bound to D-ornithine and to G418
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-GET:
GENETICIN / antibiotic*YM

ChemComp-ORX:
N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei gambiense (eukaryote)
KeywordsLYASE / ornithine decarboxylase / ODC / PLP / pyridoxal 5'-phosphate / D-ornithine / G418

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