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TitleStructural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 112, Page 685-695, Year 2003
Publish dateFeb 4, 2003 (structure data deposition date)
AuthorsMargarit, S.M. / Sondermann, H. / Hall, B.E. / Nagar, B. / Hoelz, A. / Pirruccello, M. / Bar-Sagi, D. / Kuriyan, J.
External linksCell(Cambridge,Mass. ) / PubMed:12628188
MethodsX-ray diffraction
Resolution2.18 - 3.2 Å
Structure data

PDB-1nvu:
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1nvv:
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

PDB-1nvw:
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1nvx:
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / proto-oncogene / GTP binding / Guanine nucleotide release factor / GTP-binding / Guanine-nucleotide releasing factor

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