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TitleStructural basis for the antibiotic activity of ketolides and azalides.
Journal, issue, pagesStructure, Vol. 11, Page 329-338, Year 2003
Publish dateFeb 7, 2003 (structure data deposition date)
AuthorsSchlunzen, F. / Harms, J.M. / Franceschi, F. / Hansen, H.A. / Bartels, H. / Zarivach, R. / Yonath, A.
External linksStructure / PubMed:12623020
MethodsX-ray diffraction
Resolution3.3 - 3.5 Å
Structure data

PDB-1nwx:
COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH ABT-773
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-1nwy:
COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH AZITHROMYCIN
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-773:
CETHROMYCIN / antibiotic*YM

ChemComp-ZIT:
AZITHROMYCIN / medication, antibiotic*YM

Source
  • deinococcus radiodurans (radioresistant)
KeywordsRIBOSOME / ABT-773 / MACROLIDE / KETOLIDE / 50S / RIBOSOMAL SUBUNIT / AZITHROMYCIN / RIBOSOMAL

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