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Structure paper

TitleThree-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity.
Journal, issue, pagesJ. Med. Chem., Vol. 46, Page 872-875, Year 2003
Publish dateJan 14, 2003 (structure data deposition date)
AuthorsLunn, M.L. / Hogner, A. / Stensbol, T.B. / Gouaux, E. / Egebjerg, J. / Kastrup, J.S.
External linksJ. Med. Chem. / PubMed:12593667
MethodsX-ray diffraction
Resolution1.85 - 1.9 Å
Structure data

PDB-1nnk:
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.85 A resolution. Crystallization with zinc ions.
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-1nnp:
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.9 A resolution. Crystallization without zinc ions.
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-CE2:
3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN / Ionotropic glutamate receptor GluR2 / ligand-binding core / agonist complex / agonist complex.

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