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Structure paper

TitleProduct-Assisted Catalysis in base-excision DNA Repair
Journal, issue, pagesNat. Struct. Biol., Vol. 10, Page 204-211, Year 2003
Publish dateJan 3, 2001 (structure data deposition date)
AuthorsFromme, J.C. / Bruner, S.D. / Yang, W. / Karplus, M. / Verdine, G.L.
External linksNat. Struct. Biol. / PubMed:12592398
MethodsX-ray diffraction
Resolution2.01 - 2.35 Å
Structure data

PDB-1hu0:
CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-1lwv:
Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1lww:
Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1lwy:
hOgg1 Borohydride-Trapped Intermediate without 8-oxoguanine
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-OXG:
8-OXOGUANINE

ChemComp-HOH:
WATER

ChemComp-ANG:
8-AMINOGUANINE

ChemComp-BRG:
8-BROMOGUANINE

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA / DNA REPAIR / DNA GLYCOSYLASE / PROTEIN/DNA / BOROHYDRIDE / COVALENT TRAPPING / PRODUCT-ASSISTED CATALYSIS / REACTION INTERMEDIATE / HYDROLASE-DNA COMPLEX

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