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Structure paper

TitleTwo resistance to thyroid hormone mutants with impaired hormone binding
Journal, issue, pagesMol. Endocrinol., Vol. 17, Page 643-652, Year 2003
Publish dateJan 21, 2003 (structure data deposition date)
AuthorsHuber, B.R. / Sandler, B. / West, B.L. / Cunha-Lima, S.T. / Nguyen, H.T. / Apriletti, J.W. / Baxter, J.D. / Fletterick, R.J.
External linksMol. Endocrinol. / PubMed:12554782
MethodsX-ray diffraction
Resolution2.4 - 3.1 Å
Structure data

PDB-1nq2:
Two RTH Mutants with Impaired Hormone Binding
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1nuo:
Two RTH Mutants with Impaired Hormone Binding
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-4HY:
[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID / hormone*YM

ChemComp-ARS:
ARSENIC

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR RECEPTOR / ALPHA HELICAL / LIGAND BINDING DOMAIN / HORMONE-GROWTH FACTOR RECEPTOR COMPLEX / Alpha Helix / Nuclear Receptor

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