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-Structure paper
Title | The Immunosuppressive Agent Mizoribine Monophosphate Forms a Transition State Analogue Complex with Inosine Monophosphate Dehydrogenase |
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Journal, issue, pages | Biochemistry, Vol. 42, Page 857-863, Year 2003 |
Publish date | Jun 27, 2003 (structure data deposition date) |
Authors | Gan, L. / Seyedsayamdost, M. / Shuto, S. / Matsuda, A. / Petsko, G.A. / Hedstrom, L. |
External links | Biochemistry / PubMed:12549902 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1pvn: |
Chemicals | ChemComp-K: ChemComp-MZP: ChemComp-TRS: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / Transition state analogue / IMP dehydrogenase / Mizoribine 5'-monophosphate / distal flap / general base / drug selectivity |