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TitleHumanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment
Journal, issue, pagesBIOL. PHARM. BULL., Vol. 25, Page 1537-1545, Year 2002
Publish dateJan 11, 2002 (structure data deposition date)
AuthorsHaruyama, H. / Ito, S. / Miyadai, K. / Takahashi, T. / Kawaida, R. / Takayama, T. / Hanzawa, H. / Hata, T. / Yamaguchi, J. / Yoshida-Kato, H. ...Haruyama, H. / Ito, S. / Miyadai, K. / Takahashi, T. / Kawaida, R. / Takayama, T. / Hanzawa, H. / Hata, T. / Yamaguchi, J. / Yoshida-Kato, H. / Ichikawa, K. / Ohsumi, J. / Yonehara, S. / Serizawa, N.
External linksBIOL. PHARM. BULL. / PubMed:12499636
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1it9:
CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / IMMUNOGLOBULIN / FAB / ANTI_FAS / AGONISTIC_ANTIBODY / APOPTOSIS / ANTIBODY_HUMANIZATION

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