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TitleX-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha)
Journal, issue, pagesStructure, Vol. 10, Page 1697-1702, Year 2002
Publish dateNov 19, 2002 (structure data deposition date)
AuthorsKallen, J.A. / Schlaeppi, J.M. / Bitsch, F. / Geisse, S. / Geiser, M. / Delhon, I. / Fournier, B.
External linksStructure / PubMed:12467577
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-1n83:
Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-CLR:
CHOLESTEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIPID BINDING PROTEIN / three-layered alpha helical sandwich / receptor / transcription regulation / nuclear protein / DNA binding

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