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-Structure paper
Title | Pyrrolidine-5,5-trans-lactams. 2. The use of X-ray Crystal Structure Data in the Optimisation of P3 and P4 Substituents |
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Journal, issue, pages | Org. Lett., Vol. 4, Page 4479-4482, Year 2002 |
Publish date | Oct 18, 2002 (structure data deposition date) |
Authors | Andrews, D.M. / Chaignot, H. / Coomber, B.A. / Good, A.C. / Hind, S.L. / Johnson, M.R. / Jones, P.S. / Mill, G. / Robinson, J.E. / Skarzynski, T. ...Andrews, D.M. / Chaignot, H. / Coomber, B.A. / Good, A.C. / Hind, S.L. / Johnson, M.R. / Jones, P.S. / Mill, G. / Robinson, J.E. / Skarzynski, T. / Slater, M.J. / Somers, D.O.N. |
External links | Org. Lett. / PubMed:12465917 |
Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | PDB-1n1l: |
Chemicals | ChemComp-ZN: ChemComp-TRL: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN / SERINE PROTEASE / NONSTRUCTURAL PROTEINS / COFACTOR PEPTIDE / HELICASE / INHIBITOR |