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TitleStructure of HIV-1 Reverse Transcriptase with Pre-Translocation and Post-Translocation AZTMP-Terminated DNA
Journal, issue, pagesEmbo J., Vol. 21, Page 6614-6624, Year 2002
Publish dateNov 7, 2002 (structure data deposition date)
AuthorsSarafianos, S.G. / Clark Jr., A.D. / Das, K. / Tuske, S. / Birktoft, J.J. / Ilankumaran, P. / Ramesha, A.R. / Sayer, J.M. / Jerina, D.M. / Boyer, P.L. ...Sarafianos, S.G. / Clark Jr., A.D. / Das, K. / Tuske, S. / Birktoft, J.J. / Ilankumaran, P. / Ramesha, A.R. / Sayer, J.M. / Jerina, D.M. / Boyer, P.L. / Hughes, S.H. / Arnold, E.
External linksEmbo J. / PubMed:12456667
MethodsX-ray diffraction
Resolution3 - 3.1 Å
Structure data

PDB-1n5y:
HIV-1 Reverse Transcriptase Crosslinked to Post-Translocation AZTMP-Terminated DNA (Complex P)
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-1n6q:
HIV-1 Reverse Transcriptase Crosslinked to pre-translocation AZTMP-terminated DNA (complex N)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
  • mus musculus (house mouse)
KeywordsTRANSFERASE/IMMUNE SYSTEM/DNA / HIV / translocation / nucleotide excision / drug resistance / complex P / TRANSFERASE-IMMUNE SYSTEM-DNA COMPLEX / reverse transcriptase / complex N / pre-translocation

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