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Structure paper

TitleCrystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis
Journal, issue, pagesBiochemistry, Vol. 41, Page 13309-13317, Year 2003
Publish dateMay 15, 2002 (structure data deposition date)
AuthorsGan, L. / Petsko, G.A. / Hedstrom, L.
External linksBiochemistry / PubMed:12403633
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1lrt:
CRYSTAL STRUCTURE OF TERNARY COMPLEX OF TRITRICHOMONAS FOETUS INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE: STRUCTURAL CHARACTERIZATION OF NAD+ SITE IN MICROBIAL ENZYME
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-K:
Unknown entry

ChemComp-IMP:
INOSINIC ACID

ChemComp-TAD:
BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • tritrichomonas foetus (eukaryote)
KeywordsOXIDOREDUCTASE / ternary complex / alpha-beta barrel / flexible loop / flap

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