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Structure paper

TitleCrystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors
Journal, issue, pagesCHEM. BIOL., Vol. 9, Page 1119-1128, Year 2002
Publish dateAug 29, 2002 (structure data deposition date)
AuthorsSogabe, S. / Masubuchi, M. / Sakata, K. / Fukami, T.A. / Morikami, K. / Shiratori, Y. / Ebiike, H. / Kawasaki, K. / Aoki, Y. / Shimma, N. ...Sogabe, S. / Masubuchi, M. / Sakata, K. / Fukami, T.A. / Morikami, K. / Shiratori, Y. / Ebiike, H. / Kawasaki, K. / Aoki, Y. / Shimma, N. / D'Arcy, A. / Winkler, F.K. / Banner, D.W. / Ohtsuka, T.
External linksCHEM. BIOL. / PubMed:12401496
MethodsX-ray diffraction
Resolution2.3 - 3.2 Å
Structure data

PDB-1iyk:
Crystal structure of candida albicans N-myristoyltransferase with myristoyl-COA and peptidic inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1iyl:
Crystal Structure of Candida albicans N-myristoyltransferase with Non-peptidic Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-MYA:
TETRADECANOYL-COA

ChemComp-MIM:
[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE

ChemComp-HOH:
WATER

ChemComp-R64:
(1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRIDIN-3-YLMETHYL)-AMINO]-PROPOXY}-BENZOFURAN-2-YL)-METHANONE

Source
  • candida albicans (yeast)
KeywordsTRANSFERASE

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