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Structure paper

TitleStructure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 48827-48833, Year 2002
Publish dateOct 1, 2002 (structure data deposition date)
AuthorsVenkataramani, R.N. / MacLachlan, T.K. / Chai, X. / El-Deiry, W.S. / Marmorstein, R.
External linksJ. Biol. Chem. / PubMed:12370184
MethodsX-ray diffraction
Resolution2 - 2.25 Å
Structure data

PDB-1mx2:
Structure of F71N mutant of p18INK4c
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-1mx4:
Structure of p18INK4c (F82Q)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1mx6:
Structure of p18INK4c (F92N)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordscell cycle inhibitor / Ankyrin repeats

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