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Structure paper

TitleCrystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 45219-45225, Year 2002
Publish dateApr 17, 2002 (structure data deposition date)
AuthorsAvvakumov, G.V. / Grishkovskaya, I. / Muller, Y.A. / Hammond, G.L.
External linksJ. Biol. Chem. / PubMed:12228253
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-1lhw:
CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ESM:
1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / SHBG / 2-Methoxyestradiol

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