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TitleHUMAN CYSTATHIONINE BETA-SYNTHASE IS A HEME SENSOR PROTEIN. EVIDENCE THAT THE REDOX SENSOR IS HEME AND NOT THE VICINAL CYSTEINES IN THE CXXC MOTIF SEEN IN THE CRYSTAL STRUCTURE OF THE TRUNCATED ENZYME
Journal, issue, pagesBIOCHEMISTRY, Vol. 41, Page 10454-10461, Year 2002
Publish dateJul 8, 2002 (structure data deposition date)
AuthorsTaoka, S. / Lepore, B.W. / Kabil, O. / Ojha, S. / Ringe, D. / Banerjee, R.
External linksBIOCHEMISTRY / PubMed:12173932
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1m54:
CYSTATHIONINE-BETA SYNTHASE: REDUCED VICINAL THIOLS
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / PLP PROTEIN FOLD TYPE II (TRYPTOPHAN SYNTHASE) / PLP AND HEME BOUND TO PROTEIN / REDUCED VICINAL CYSTEINES

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