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TitleHigh Resolution Crystal Structure of the Human Pdk1 Catalytic Domain Defines the Regulatory Phosphopeptide Docking Site
Journal, issue, pagesEmbo J., Vol. 21, Page 4219-, Year 2003
Publish dateJul 23, 2002 (structure data deposition date)
AuthorsBiondi, R.M. / Komander, D. / Thomas, C.C. / Lizcano, J.M. / Deak, M. / Alessi, D.R. / Van Aalten, D.M.F.
External linksEmbo J. / PubMed:12169624
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1h1w:
High resolution crystal structure of the human PDK1 catalytic domain
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE / PKA / AGC KINASE ACTIVATION / PIF-POCKET / PI3-KINASE SIGNALLING / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING

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