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-Structure paper
Title | Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI). |
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Journal, issue, pages | J. Med. Chem., Vol. 45, Page 3246-3256, Year 2002 |
Publish date | Jun 4, 2002 (structure data deposition date) |
![]() | Miller, W.H. / Seefeld, M.A. / Newlander, K.A. / Uzinskas, I.N. / Burgess, W.J. / Heerding, D.A. / Yuan, C.C. / Head, M.S. / Payne, D.J. / Rittenhouse, S.F. ...Miller, W.H. / Seefeld, M.A. / Newlander, K.A. / Uzinskas, I.N. / Burgess, W.J. / Heerding, D.A. / Yuan, C.C. / Head, M.S. / Payne, D.J. / Rittenhouse, S.F. / Moore, T.D. / Pearson, S.C. / Berry, V. / DeWolf Jr., W.E. / Keller, P.M. / Polizzi, B.J. / Qiu, X. / Janson, C.A. / Huffman, W.F. |
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Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-1lx6: ![]() PDB-1lxc: |
Chemicals | ![]() ChemComp-NAD: ![]() ChemComp-ZAM: ![]() ChemComp-HOH: ![]() ChemComp-AYM: |
Source |
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![]() | OXIDOREDUCTASE / FABI / ENOYL REDUCTASE |