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TitleComprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
Journal, issue, pagesJ. Mol. Biol., Vol. 320, Page 415-428, Year 2002
Publish dateMar 15, 2002 (structure data deposition date)
AuthorsVajdos, F.F. / Adams, C.W. / Breece, T.N. / Presta, L.G. / de Vos, A.M. / Sidhu, S.S.
External linksJ. Mol. Biol. / PubMed:12079396
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-1l7i:
Crystal Structure of the anti-ErbB2 Fab2C4
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Ig domain / Fab fragment

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