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TitleLigand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 30892-30900, Year 2002
Publish dateApr 7, 2002 (structure data deposition date)
AuthorsPazy, Y. / Kulik, T. / Bayer, E.A. / Wilchek, M. / Livnah, O.
External linksJ. Biol. Chem. / PubMed:12055191
MethodsX-ray diffraction
Resolution1.95 - 2.9 Å
Structure data

PDB-1lcv:
streptavidin-norbiotin complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1lcw:
streptavidin-homobiotin complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1lcz:
streptavidin-BCAP complex
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-1ldo:
avidin-norbioitn complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1ldq:
avidin-homobiotin complex
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1lel:
The avidin BCAP complex
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-SNR:
NORBIOTIN

ChemComp-HOH:
WATER

ChemComp-SHM:
HOMOBIOTIN

ChemComp-BH7:
E-AMINO BIOTINYL CAPROIC ACID

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • streptomyces avidinii (bacteria)
  • gallus gallus (chicken)
KeywordsUNKNOWN FUNCTION / avidin / streptavidin / biotin / biotin-analogues / high affinity systems / ligand exchange

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