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Structure paper

TitleMinor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
Journal, issue, pagesJ. Mol. Biol., Vol. 319, Page 449-461, Year 2002
Publish dateDec 11, 2001 (structure data deposition date)
AuthorsSundberg, E.J. / Sawicki, M.W. / Southwood, S. / Andersen, P.S. / Sette, A. / Mariuzza, R.A.
External linksJ. Mol. Biol. / PubMed:12051920
MethodsX-ray diffraction
Resolution1.93 - 2.4 Å
Structure data

PDB-1klg:
Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1klu:
Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • staphylococcus aureus (bacteria)
KeywordsIMMUNE SYSTEM/TOXIN / HLA-DR1/TPI / enterotoxin C3 / human melanoma antigen / CD4+ T cells / IMMUNE SYSTEM-TOXIN COMPLEX

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