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TitleStructure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution.
Journal, issue, pagesFEBS Lett., Vol. 520, Page 13-17, Year 2002
Publish dateOct 4, 2001 (structure data deposition date)
AuthorsPavao, F. / Castilho, M.S. / Pupo, M.T. / Dias, R.L. / Correa, A.G. / Fernandes, J.B. / da Silva, M.F. / Mafezoli, J. / Vieira, P.C. / Oliva, G.
External linksFEBS Lett. / PubMed:12044862
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-1k3t:
Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-BRZ:
6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE

ChemComp-HOH:
WATER

Source
  • trypanosoma cruzi (eukaryote)
KeywordsOXIDOREDUCTASE / Apo-Protein / gGAPDH-Chalepin complex / glycosome / Trypanosoma cruzi

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