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Structure paper

TitleCrystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism.
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 17161-17169, Year 2002
Publish dateDec 9, 2001 (structure data deposition date)
AuthorsTrivedi, V. / Gupta, A. / Jala, V.R. / Saravanan, P. / Rao, G.S. / Rao, N.A. / Savithri, H.S. / Subramanya, H.S.
External linksJ. Biol. Chem. / PubMed:11877399
MethodsX-ray diffraction
Resolution1.93 - 2.7 Å
Structure data

PDB-1kkj:
Crystal Structure of Serine Hydroxymethyltransferase from B.stearothermophilus
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-1kkp:
Crystal Structure of Serine Hydroxymethyltransferase complexed with Serine
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-1kl1:
Crystal Structure of Serine Hydroxymethyltransferase Complexed with Glycine
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-1kl2:
Crystal Structure of Serine Hydroxymethyltransferase Complexed with Glycine and 5-formyl tetrahydrofolate
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-SER:
SERINE

ChemComp-GLY:
GLYCINE

ChemComp-FON:
N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid

Source
  • geobacillus stearothermophilus (bacteria)
KeywordsTRANSFERASE / SHMT PLP tetrahydrofolate

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