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TitleSugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme.
Journal, issue, pagesJ. Mol. Biol., Vol. 315, Page 1099-1110, Year 2002
Publish dateNov 13, 2001 (structure data deposition date)
AuthorsBertrand, T. / Briozzo, P. / Assairi, L. / Ofiteru, A. / Bucurenci, N. / Munier-Lehmann, H. / Golinelli-Pimpaneau, B. / Barzu, O. / Gilles, A.M.
External linksJ. Mol. Biol. / PubMed:11827479
MethodsX-ray diffraction
Resolution1.9 - 2.3 Å
Structure data

PDB-1kdo:
CYTIDINE MONOPHOSPHATE KINASE FROM E. COLI IN COMPLEX WITH CYTIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1kdp:
CYTIDINE MONOPHOSPHATE KINASE FROM E. COLI IN COMPLEX WITH 2'-DEOXY-CYTIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1kdr:
CYTIDINE MONOPHOSPHATE KINASE FROM E.COLI IN COMPLEX WITH ARA-CYTIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-1kdt:
CYTIDINE MONOPHOSPHATE KINASE FROM E.COLI IN COMPLEX WITH 2',3'-DIDEOXY-CYTIDINE MONOPHOSPHATE
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-DCM:
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE

ChemComp-CAR:
CYTOSINE ARABINOSE-5'-PHOSPHATE

ChemComp-DOC:
2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / NUCLEOTIDE MONOPHOSPHATE KINASE

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