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TitleStructure-based design and protein X-ray analysis of a protein kinase inhibitor.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 12, Page 221-224, Year 2002
Publish dateAug 31, 2001 (structure data deposition date)
AuthorsFuret, P. / Meyer, T. / Strauss, A. / Raccuglia, S. / Rondeau, J.M.
External linksBioorg. Med. Chem. Lett. / PubMed:11755359
MethodsX-ray diffraction
Resolution1.53 Å
Structure data

PDB-1jvp:
Crystal structure of human CDK2 (unphosphorylated) in complex with PKF049-365
Method: X-RAY DIFFRACTION / Resolution: 1.53 Å

Chemicals

ChemComp-89E:
3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Protein Kinase / Cell Division / Cell cycle / Enzyme Inhibitors / Drug design

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