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TitleCross-Reactive Binding of Cyclic Peptides to an Anti-Tgf Alpha Antibody Fab Fragment: An X-Ray Structural and Thermodynamic Analysis
Journal, issue, pagesJ. Mol. Biol., Vol. 314, Page 293-, Year 2001
Publish dateJul 12, 2000 (structure data deposition date)
AuthorsHahn, M. / Winkler, D. / Welfle, K. / Misselwitz, R. / Welfle, H. / Wessner, H. / Zahn, G. / Scholz, C. / Seifert, M. / Harkins, R. ...Hahn, M. / Winkler, D. / Welfle, K. / Misselwitz, R. / Welfle, H. / Wessner, H. / Zahn, G. / Scholz, C. / Seifert, M. / Harkins, R. / Schneider-Mergener, J. / Hoehne, W.
External linksJ. Mol. Biol. / PubMed:11718562
MethodsX-ray diffraction
Resolution1.9 - 1.95 Å
Structure data

PDB-1e4w:
crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-1e4x:
crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / COMPLEX (ANTIBODY-ANTIGEN) / CROSS-REACTIVITY / PROTEIN-PEPTIDE RECOGNITION

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