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Structure paper

TitleCrystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture.
Journal, issue, pagesEMBO J., Vol. 20, Page 6191-6202, Year 2001
Publish dateAug 28, 2001 (structure data deposition date)
AuthorsPeneff, C. / Ferrari, P. / Charrier, V. / Taburet, Y. / Monnier, C. / Zamboni, V. / Winter, J. / Harnois, M. / Fassy, F. / Bourne, Y.
External linksEMBO J. / PubMed:11707391
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-1jv1:
CRYSTAL STRUCTURE OF HUMAN AGX1 COMPLEXED WITH UDPGLCNAC
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1jv3:
CRYSTAL STRUCTURE OF HUMAN AGX1 COMPLEXED WITH UDPGALNAC
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1jvd:
CRYSTAL STRUCTURE OF HUMAN AGX2 COMPLEXED WITH UDPGLCNAC
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1jvg:
CRYSTAL STRUCTURE OF HUMAN AGX2 COMPLEXED WITH UDPGALNAC
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-UD1:
URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE

ChemComp-HOH:
WATER

ChemComp-UD2:
URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / NUCLEOTIDYLTRANSFERASE / ALTERNATIVE SPLICING

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