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Structure paper

TitleGetting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT.
Journal, issue, pagesStructure, Vol. 9, Page 977-985, Year 2001
Publish dateDec 7, 2000 (structure data deposition date)
AuthorsMartin, J.L. / Begun, J. / McLeish, M.J. / Caine, J.M. / Grunewald, G.L.
External linksStructure / PubMed:11591352
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-1hnn:
CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-SKF:
1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / methyltransferase / adrenaline synthesis / S-adenosyl methionine

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