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Structure paper

TitleStructural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Journal, issue, pagesBiochemistry, Vol. 40, Page 8756-8764, Year 2001
Publish dateMay 16, 2001 (structure data deposition date)
AuthorsBurk, D.L. / Hon, W.C. / Leung, A.K. / Berghuis, A.M.
External linksBiochemistry / PubMed:11467935
MethodsX-ray diffraction
Resolution2.2 - 3.2 Å
Structure data

PDB-1j7i:
Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Apoenzyme
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-1j7l:
Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Complex
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1j7u:
Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Complex
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • enterococcus faecalis (bacteria)
KeywordsTRANSFERASE / antibiotic resistance / kinase / ATP-binding

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