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Structure paper

TitleCrystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem
Journal, issue, pagesJ. Mol. Biol., Vol. 310, Page 859-, Year 2001
Publish dateFeb 17, 2001 (structure data deposition date)
AuthorsPernot, L. / Frenois, F. / Rybkine, T. / L'Hermite, G. / Petrella, S. / Delettre, J. / Jarlier, V. / Collatz, E. / Sougakoff, W.
External linksJ. Mol. Biol. / PubMed:11453693
MethodsX-ray diffraction
Resolution1.8 - 2 Å
Structure data

PDB-1h8y:
Crystal structure of the class D beta-lactamase OXA-13 in complex with meropenem
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1h8z:
Crystal structure of the class D beta-lactamase OXA-13
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MER:
(4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d / antibiotic*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / BETA-LACTAMASE / CLASS D / OXA-13 / MEROPENEM / ACYL- ENZYME / OXACILLINASE

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