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Structure paper

TitleStructure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII.
Journal, issue, pagesBlood, Vol. 98, Page 13-19, Year 2001
Publish dateJul 21, 2001 (structure data deposition date)
AuthorsSpiegel Jr., P.C. / Jacquemin, M. / Saint-Remy, J.M. / Stoddard, B.L. / Pratt, K.P.
External linksBlood / PubMed:11418455
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1iqd:
Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/BLOOD CLOTTING / FACTOR VIII / C2 DOMAIN / ANTIBODY / BLOOD COAGULATION / INHIBITOR / BO2C11 / IMMUNE SYSTEM-BLOOD CLOTTING COMPLEX

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