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Structure paper

TitleNADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 29163-29170, Year 2001
Publish dateMay 29, 2001 (structure data deposition date)
AuthorsHubbard, P.A. / Shen, A.L. / Paschke, R. / Kasper, C.B. / Kim, J.J.
External linksJ. Biol. Chem. / PubMed:11371558
MethodsX-ray diffraction
Resolution1.8 - 2.7 Å
Structure data

PDB-1j9z:
CYPOR-W677G
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1ja0:
CYPOR-W677X
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-1ja1:
CYPOR-Triple Mutant
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

Source
  • rattus norvegicus (Norway rat)
KeywordsOXIDOREDUCTASE / NADPH-Cytochrome P450 reductase

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