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Title | Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 98, Page 4904-4909, Year 2001 |
Publish date | Feb 13, 2001 (structure data deposition date) |
Authors | Sack, J.S. / Kish, K.F. / Wang, C. / Attar, R.M. / Kiefer, S.E. / An, Y. / Wu, G.Y. / Scheffler, J.E. / Salvati, M.E. / Krystek Jr., S.R. ...Sack, J.S. / Kish, K.F. / Wang, C. / Attar, R.M. / Kiefer, S.E. / An, Y. / Wu, G.Y. / Scheffler, J.E. / Salvati, M.E. / Krystek Jr., S.R. / Weinmann, R. / Einspahr, H.M. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:11320241 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-1i37: PDB-1i38: |
Chemicals | ChemComp-DHT: ChemComp-HOH: |
Source |
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Keywords | HORMONE/GROWTH FACTOR / ANDROGEN RECEPTOR / STEROID RECEPTOR / NUCLEAR RECEPTOR / TRANSCRIPTION REGULATION / LIGAND-BINDING DOMAIN / HORMONE-GROWTH FACTOR COMPLEX |