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TitleCrystal Structure Analysis of Warfarin Binding to Human Serum Albumin: Anatomy of Drug Site I
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 22804-, Year 2001
Publish dateMar 23, 2001 (structure data deposition date)
AuthorsPetitpas, I. / Bhattacharya, A.A. / Twine, S. / East, M. / Curry, S.
External linksJ. Biol. Chem. / PubMed:11285262
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1h9z:
Human Serum Albumin Complexed With Myristic Acid and the R-(+) enantiomer of warfarin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1ha2:
Human Serum Albumin Complexed With Myristic Acid and the S-(-) enantiomer of warfarin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-MYR:
MYRISTIC ACID

ChemComp-RWF:
R-WARFARIN

ChemComp-HOH:
WATER

ChemComp-SWF:
S-WARFARIN / medication, anticoagulant*YM

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / SERUM PROTEIN / DRUG BINDING / ANTI-COAGULANT

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