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Structure paper

TitleHuman cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping.
Journal, issue, pagesNat. Struct. Biol., Vol. 8, Page 316-320, Year 2001
Publish dateNov 22, 2000 (structure data deposition date)
AuthorsJanowski, R. / Kozak, M. / Jankowska, E. / Grzonka, Z. / Grubb, A. / Abrahamson, M. / Jaskolski, M.
External linksNat. Struct. Biol. / PubMed:11276250
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1g96:
HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydrolase inhibitor / human cystatin C dimer / 3D domain swapping / amyloid formation / inhibitor of C1 and C13 cysteine proteases / AMYLOID ANGIOPATHY AND CEREBRAL HEMORRHAGE

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