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TitleIdentification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 57, Page 536-544, Year 2001
Publish dateJan 22, 2001 (structure data deposition date)
AuthorsMolteni, V. / Greenwald, J. / Rhodes, D. / Hwang, Y. / Kwiatkowski, W. / Bushman, F.D. / Siegel, J.S. / Choe, S.
External linksActa Crystallogr. ,Sect. D / PubMed:11264582
MethodsX-ray diffraction
Resolution1.7 - 2.3 Å
Structure data

PDB-1hyv:
HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1hyz:
HIV INTEGRASE CORE DOMAIN COMPLEXED WITH A DERIVATIVE OF TETRAPHENYL ARSONIUM.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-TTA:
TETRAPHENYL-ARSONIUM

ChemComp-HOH:
WATER

ChemComp-TTO:
(3,4-DIHYDROXY-PHENYL)-TRIPHENYL-ARSONIUM

Source
  • human immunodeficiency virus 1
KeywordsTRANSFERASE / DNA INTEGRATION

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