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Structure paper

TitleStructural determinants for regulation of phosphodiesterase by a G protein at 2.0 A.
Journal, issue, pagesNature, Vol. 409, Page 1071-1077, Year 2001
Publish dateSep 5, 2000 (structure data deposition date)
AuthorsSlep, K.C. / Kercher, M.A. / He, W. / Cowan, C.W. / Wensel, T.G. / Sigler, P.B.
External linksNature / PubMed:11234020
MethodsX-ray diffraction
Resolution1.94 - 2.3 Å
Structure data

PDB-1fqi:
RGS9 RGS DOMAIN
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-1fqj:
CRYSTAL STRUCTURE OF THE HETEROTRIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, THE GAMMA SUBUNIT OF PHOSPHODIESTERASE AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(PDEGAMMA)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-1fqk:
CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF THE RGS DOMAIN OF RGS9, AND THE GT/I1 CHIMERA ALPHA SUBUNIT [(RGS9)-(GT/I1ALPHA)-(GDP)-(ALF4-)-(MG2+)]
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • bos taurus (domestic cattle)
  • rattus norvegicus (Norway rat)
KeywordsSIGNALING PROTEIN / RGS9 / Phototransduction / rod / RGS / GAP / transducin / effector / PDEgamma / G Protein / phosphodiesterase

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