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Structure paper

TitleDramatic structural and thermodynamic consequences of repacking a protein's hydrophobic core.
Journal, issue, pagesStructure Fold. Des., Vol. 8, Page 1319-1328, Year 2000
Publish dateJun 8, 2000 (structure data deposition date)
AuthorsWillis, M.A. / Bishop, B. / Regan, L. / Brunger, A.T.
External linksStructure Fold. Des. / PubMed:11188696
MethodsX-ray diffraction
Resolution1.9 - 2.25 Å
Structure data

PDB-1f4m:
P3(2) CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-1f4n:
C2 CRYSTAL STRUCTURE OF ALA2ILE2-6, A VERSION OF ROP WITH A REPACKED HYDROPHOBIC CORE AND A NEW FOLD.
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION / Rop / dimer / homodimer / helix-turn-helix / transcription regulation / hydrophobic core packing / thermodynamic stability

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