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TitleSubstrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis.
Journal, issue, pagesStructure Fold. Des., Vol. 8, Page 1309-1318, Year 2000
Publish dateSep 8, 2000 (structure data deposition date)
AuthorsHeroux, A. / White, E.L. / Ross, L.J. / Kuzin, A.P. / Borhani, D.W.
External linksStructure Fold. Des. / PubMed:11188695
MethodsX-ray diffraction
Resolution1.05 Å
Structure data

PDB-1fsg:
TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH 9-DEAZAGUANINE, ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE (PRPP) AND TWO MG2+ IONS
Method: X-RAY DIFFRACTION / Resolution: 1.05 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-PRP:
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose

ChemComp-9DG:
9-DEAZAGUANINE

ChemComp-HOH:
WATER

Source
  • toxoplasma gondii (eukaryote)
KeywordsTRANSFERASE / GLYCOSYLTRANSFERASE / PURINE SALVAGE

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