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Structure paper

TitleMechanistic inferences from the crystal structure of fumarylacetoacetate hydrolase with a bound phosphorus-based inhibitor.
Journal, issue, pagesJ. Biol. Chem., Vol. 276, Page 15284-15291, Year 2001
Publish dateJan 21, 2001 (structure data deposition date)
AuthorsBateman, R.L. / Bhanumoorthy, P. / Witte, J.F. / McClard, R.W. / Grompe, M. / Timm, D.E.
External linksJ. Biol. Chem. / PubMed:11154690
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-1hyo:
CRYSTAL STRUCTURE OF FUMARYLACETOACETATE HYDROLASE COMPLEXED WITH 4-(HYDROXYMETHYLPHOSPHINOYL)-3-OXO-BUTANOIC ACID
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HBU:
4-[HYDROXY-[METHYL-PHOSPHINOYL]]-3-OXO-BUTANOIC ACID

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / beta-sandwich roll

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