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Structure paper

TitleInsights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 103, Page 467-479, Year 2000
Publish dateOct 13, 2000 (structure data deposition date)
AuthorsSomers, W.S. / Tang, J. / Shaw, G.D. / Camphausen, R.T.
External linksCell(Cambridge,Mass. ) / PubMed:11081633
MethodsX-ray diffraction
Resolution1.5 - 3.4 Å
Structure data

PDB-1g1q:
Crystal structure of P-selectin lectin/EGF domains
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1g1r:
Crystal structure of P-selectin lectin/EGF domains complexed with SLeX
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-1g1s:
P-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH PSGL-1 PEPTIDE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1g1t:
CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-SR:
STRONTIUM ION

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MEMBRANE PROTEIN / Lectin / EGF / Adhesion molecule / SLeX / selectin / sulphated

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