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TitleStructures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 56, Page 1385-1394, Year 2000
Publish dateJan 5, 1999 (structure data deposition date)
AuthorsKryger, G. / Harel, M. / Giles, K. / Toker, L. / Velan, B. / Lazar, A. / Kronman, C. / Barak, D. / Ariel, N. / Shafferman, A. ...Kryger, G. / Harel, M. / Giles, K. / Toker, L. / Velan, B. / Lazar, A. / Kronman, C. / Barak, D. / Ariel, N. / Shafferman, A. / Silman, I. / Sussman, J.L.
External linksActa Crystallogr. ,Sect. D / PubMed:11053835
MethodsX-ray diffraction
Resolution2.76 - 2.9 Å
Structure data

PDB-1b41:
HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH FASCICULIN-II, GLYCOSYLATED PROTEIN
Method: X-RAY DIFFRACTION / Resolution: 2.76 Å

PDB-1f8u:
CRYSTAL STRUCTURE OF MUTANT E202Q OF HUMAN ACETYLCHOLINESTERASE COMPLEXED WITH GREEN MAMBA VENOM PEPTIDE FASCICULIN-II
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • dendroaspis angusticeps (eastern green mamba)
KeywordsHYDROLASE/TOXIN / SERINE ESTERASE / HUMAN-ACETYLCHOLINESTERASE / HYDROLASE / SNAKE TOXIN / HYDROLASE-TOXIN COMPLEX / HUMAN ACETYLCHOLINESTERASE / HYDROLASE/HYDROLASE INHIBITOR

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