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Structure paper

TitleCrystal structure of human cathepsin V.
Journal, issue, pagesBiochemistry, Vol. 39, Page 12543-12551, Year 2000
Publish dateJul 30, 2000 (structure data deposition date)
AuthorsSomoza, J.R. / Zhan, H. / Bowman, K.K. / Yu, L. / Mortara, K.D. / Palmer, J.T. / Clark, J.M. / McGrath, M.E.
External linksBiochemistry / PubMed:11027133
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-1fh0:
CRYSTAL STRUCTURE OF HUMAN CATHEPSIN V COMPLEXED WITH AN IRREVERSIBLE VINYL SULFONE INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-0IW:
Nalpha-[(4-methylpiperazin-1-yl)carbonyl]-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-phenylalaninamide

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE inhibitor / cathepsin / papain / protease / cancer / HYDROLASE-HYDROLASE inhibitor complex

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