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Structure paper

Titlevon Willebrand factor conformation and adhesive function is modulated by an internalized water molecule.
Journal, issue, pagesNat. Struct. Biol., Vol. 7, Page 881-884, Year 2000
Publish dateAug 23, 2000 (structure data deposition date)
AuthorsCelikel, R. / Ruggeri, Z.M. / Varughese, K.I.
External linksNat. Struct. Biol. / PubMed:11017197
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1fns:
CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR (VWF) A1 DOMAIN I546V MUTANT IN COMPLEX WITH THE FUNCTION BLOCKING FAB NMC4
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / VON WILLEBRAND FACTOR / GLYCOPROTEIN IBA (A:ALPHA) BINDING / COMPLEX (WILLEBRAND-IMMUNOGLOBULIN) / BLOOD COAGULATION TYPE 2B VON WILLEBRAND DISEASE

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