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TitleThe structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity
Journal, issue, pagesNat. Struct. Biol., Vol. 7, Page 762-765, Year 2000
Publish dateAug 3, 2000 (structure data deposition date)
AuthorsWaugh, S.M. / Harris, J.L. / Fletterick, R. / Craik, C.S.
External linksNat. Struct. Biol. / PubMed:10966646
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1fi8:
RAT GRANZYME B [N66Q] COMPLEXED TO ECOTIN [81-84 IEPD]
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • escherichia coli (E. coli)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / complex (serine protease-inhibitor) / protease substrate interactions / beta strand structure / chymotrypsin fold / granzyme B / ecotin / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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