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TitleThe atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.
Journal, issue, pagesJ. Mol. Biol., Vol. 299, Page 181-197, Year 2000
Publish dateMar 2, 2000 (structure data deposition date)
AuthorsMeining, W. / Mortl, S. / Fischer, M. / Cushman, M. / Bacher, A. / Ladenstein, R.
External linksJ. Mol. Biol. / PubMed:10860731
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-1ejb:
LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-INJ:
5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE / Lumazine synthase / Saccharomyces cerevisiae / X-ray structure analysis / Inhibitor complex / Vitamin biosynthesis

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