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Structure paper

TitleDesign, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.
Journal, issue, pagesJ. Mol. Biol., Vol. 299, Page 169-179, Year 2000
Publish dateMar 9, 2000 (structure data deposition date)
AuthorsLandar, A. / Curry, B. / Parker, M.H. / DiGiacomo, R. / Indelicato, S.R. / Nagabhushan, T.L. / Rizzi, G. / Walter, M.R.
External linksJ. Mol. Biol. / PubMed:10860730
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1eku:
CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CYTOKINE / PROTEIN ENGINEERING / INTERFERON

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